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edit Sorting nexin associated golgi protein 1 Identifiers Symbols SNAG1; MGC150827; MGC150829; SH3PX2; SH3PXD3B; SNX18 External IDs MGI: 2137642 HomoloGene: 14164 GeneCards: SNAG1 Gene Gene Ontology Molecular function • protein binding • phosphoinositide binding Biological process • cell communication • protein transport Sources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 112574 170625 Ensembl ENSG00000178996 ENSMUSG00000042364 UniProt Q96RF0 Q91ZR2 RefSeq (mRNA) NM_052870 NM_130796 RefSeq (protein) NP_443102 NP_570614 Location (UCSC) Chr 5: 53.85 - 53.88 Mb Chr 13: 114.71 - 114.74 Mb PubMed search [1] [2] Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.[1][2][3] This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.[3] References ^ Seet LF, Hong W (Sep 2006). "The Phox (PX) domain proteins and membrane traffic". Biochim Biophys Acta 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399.  ^ Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J (Sep 2007). "A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells". FEBS Lett 581 (23): 4455–62. doi:10.1016/j.febslet.2007.08.025. PMID 17761170.  ^ a b "Entrez Gene: SNAG1 sorting nexin associated golgi protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574.  Further reading Worby CA, Dixon JE (2003). "Sorting out the cellular functions of sorting nexins.". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558.  Xu Y, Seet LF, Hanson B, Hong W (2002). "The Phox homology (PX) domain, a new player in phosphoinositide signalling.". Biochem. J. 360 (Pt 3): 513–30. doi:10.1042/0264-6021:3600513. PMID 11736640.  Ozyildirim AM, Wistow GJ, Gao J, et al. (2005). "The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts.". Invest. Ophthalmol. Vis. Sci. 46 (5): 1572–80. doi:10.1167/iovs.04-1380. PMID 15851553.  Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  Schulze WX, Mann M (2004). "A novel proteomic screen for peptide-protein interactions.". J. Biol. Chem. 279 (11): 10756–64. doi:10.1074/jbc.M309909200. PMID 14679214.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  Teasdale RD, Loci D, Houghton F, et al. (2001). "A large family of endosome-localized proteins related to sorting nexin 1.". Biochem. J. 358 (Pt 1): 7–16. doi:10.1042/0264-6021:3580007. PMID 11485546.  This article on a gene on chromosome 5 is a stub. You can help Wikipedia by expanding it. v • d • e v • d • e Sorting nexins SNX-BAR SNX1 · SNX2 · SNX4 · SNX5 · SNX6 · SNX7 · SNX8 · SNX9 · SNX18 · SNX30 · SNX32 · SNX33 SNX-PX SNX3 · SNX10 · SNX11 · SNX12 · SNX16 · SNX20 · SNX21 · SNX22 · SNX24 · SNX29 SNX-Other SNX13 · SNX14 · SNX15 · SNX17 · SNX19 · SNX23 · SNX25 · SNX26 · SNX27 · SNX28 · SNX31 Related articles PX domain · BAR domain · Retromer B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)